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Our approach

Open minds.
Grounded intentions.

Amsterdam · AscentFive

AscentFive is an independent 5-MeO-DMT practice. Exploring the inner world begins with the way we approach it: with curiosity, respect, and space for the unknown.

Flowing sculptural forms in blue and silverA shift in perspective

A way of being.
A way of relating.

Non-duality invites us to question the sense that we are separate from the world around us.

For AscentFive, this is a starting point for inquiry. A way to explore attention, identity and connection, without requiring anyone to adopt a particular belief.

The practice’s interests span consciousness, 5-MeO-DMT, and the process of integration. The thread running through them is the same: how we understand ourselves, and how that understanding shapes the way we live.

From insight to everyday life

“What matters is not only
what we experience, but
how we live afterwards.”

The AscentFive philosophy

No standard
session.

The approach is personalised to each participant, and so is the protocol.

Sensitivity to 5-MeO-DMT differs from one person to the next. The protocol of administration follows from that rather than from a fixed programme, and it is set with the person it is for.

Two broad forms are used, separately or together: low-dose work and full-release sessions. Which of them a process draws on is decided in conversation, before anything is agreed.

Openness and
discernment.

Personal experience and scientific evidence answer different questions.

5-MeO-DMT is a potent psychedelic studied in early clinical research. Reports of changes in mood or a sense of connection do not establish a guaranteed outcome, and research in carefully controlled settings cannot simply be applied to every other setting.

Experiences may also be overwhelming or distressing. Health history, medication interactions and psychological wellbeing matter. Qualified medical advice is essential for personal health decisions; this website is not a substitute for it.

Further readingICEERS: background and risk information Clinical research: evidence and limitations F.I.V.E.: training and education
A few starting points

Questions
are welcome.

Is this Bufo, or toad medicine?

No. “Bufo” names a toad, and its secretion contains more than a dozen compounds besides 5-MeO-DMT. AscentFive’s subject is the defined synthetic compound. See Bufo and 5-MeO-DMT for the difference and why it matters.

What does non-duality mean?

It is a perspective that questions the usual division between self and world. Different philosophical and contemplative traditions explore it in different ways. You do not need to agree with a particular interpretation to be curious about it.

What is integration?

Integration is the ongoing process of making sense of an experience and considering its place in everyday life. It can involve reflection, conversation and attention to relationships and daily habits.

Are experiences or outcomes guaranteed?

No. Subjective experiences vary, and meaningful experiences can also be challenging. Claims of complete safety or guaranteed healing should be approached critically.

How can I learn more about the practice?

Start with a question. Contact AscentFive to ask about the approach, practitioner background or the information you would need to make an informed decision.

Room for your questions

Let’s begin with
a conversation.

Get in touch