Two molecules,
four characters apart.

One is not
a kind of the other.

5-MeO-DMT is 5-methoxy-N,N-dimethyltryptamine. DMT, used on its own, normally means N,N-dimethyltryptamine.

The prefix is the whole difference in writing: a methoxy group at the fifth position. That is why the names look like variants of each other, and it is also why they are not. They are distinct compounds, and this library treats them as such throughout.

Both are tryptamines and both are potent. Beyond that, nothing should be assumed to carry across from one to the other without evidence that it does.

A study of one
is not evidence about the other.

This is the practical consequence, and it is the reason the page exists.

A DMT study cannot automatically be used as evidence for 5-MeO-DMT. Anyone reading about duration, interactions, adverse effects or contraindications needs to know which molecule the paper was about, because the answers do not transfer.

The same caution applies within 5-MeO-DMT research. A trial of a manufactured formulation does not establish equivalent effects for a cartridge of unknown composition or for a biological secretion, and numerical amounts across products are not interchangeable doses.

Someone checking whether a medication is safe to combine, and reading the wrong literature to do it, has not been careful. They have been careful about the wrong thing.

Same compound,
different words.

Several names in circulation refer to the same molecule, or to something narrower than people assume.

Mebufotenin

A name used for 5-MeO-DMT in current clinical research. The same compound, not a related one.

GH001, BPL-003

Specific investigational formulations. They are not interchangeable names for all preparations of 5-MeO-DMT, and each has its own route and profile.

Bufo, toad venom

A secretion containing more than a dozen compounds, of which 5-MeO-DMT is one. Not another word for the purified compound.

Describe an experience
we have not reviewed.

You will find no comparison here of what the two are like.

Accounts contrasting the two circulate widely, and some of them may well be accurate. They are not what this library has reviewed, and writing them up here would be repeating an impression as though it were a finding — which is the habit this page is arguing against.

What the research does report about 5-MeO-DMT specifically, including how long it lasts and what is measured, is set out separately.